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The pilot clinical trial was a blinded, single-site, pharmacokinetic/pharmacodynamic study assessing two single, ascending doses of NBI-77860 against placebo in adult females with refractory CAH.
Pharmacokinetic/pharmacodynamic investigation of colistin against Pseudomonas aeruginosa using an in vitro model.
To address the full spectrum of R&D related challenges, Rosa offers customized approaches: classic pharmacokinetic/pharmacodynamic (PK/PD) models and Rosa's innovative PhysioPD[TM] models.
Rosa offers both PhysioPD(TM) Research Platforms and classic pharmacokinetic/pharmacodynamic (PK/PD) models.
However, the cost of anti-infective drug development can be dramatically lowered by applying pharmacometric concepts and selecting some key experiments based on pharmacokinetic/pharmacodynamic (PK/PD) concepts.
14 Pharmacokinetic/Pharmacodynamic Modelling: Simultaneous Measurement of Concentrations and Effect
Pre-Clinical Safety and Prolonged Pharmacokinetic/Pharmacodynamic (PK/PD) Properties of a Recombinant Fusion Protein Linking Activated Coagulation Factor VII with Albumin (rVIIa-FP)(S.
8221; The talk will describe the use of microdosing and AMS data for development of both pharmacokinetic/pharmacodynamics and mechanistic physiological models, and how the resulting new insights can improve drug development practice in pediatric and other sensitive populations.