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7,49) An additional advantage of cross-sectional imaging is the ability to screen for extraluminal malignancies that can arise in Peutz-Jeghers syndrome.
LKB1 is a serine/threonine protein kinase which was first discovered in the study of Peutz-Jeghers syndrome (Hemminki et al.
The mucocutaneous pigmentation due to melanin deposition of Peutz-Jeghers syndrome is associated with increased morbidity from intestinal polyps and increased risk of invasive carcinoma.
Genetic syndromes are: familial atypical multiple malignant melanoma (FAMMM); Peutz-Jeghers syndrome (PJS); BRCA1 and BRCA2 germ-line mutations in breast and ovarian hereditary cancer syndromes; hereditary nonpolyposis colorectal cancer; familial adenomatous polyposis; and Li-Fraumeni syndrome [3-4].
Peutz-Jeghers syndrome and PLE were considered as part of the differential diagnosis, and further investigation was needed.
There are many hereditary syndromes that present a risk for the development of colon cancer including familial adenomatous polyposis (FAP) coli, hereditary nonpolyposis colorectal cancer (HNPCC), Peutz-Jeghers syndrome, Gardner's syndrome, and others.
About HCCA The mission of the HCCA is the prevention of colon cancer caused by the inherited syndromes of colon cancer including: Familial Adenomatous Polyposis (FAP), Gardner syndrome, Juvenile Familial Polyposis, Hereditary Non Polyposis Colorectal Cancer (HNPCC), Attenuated Adenomatous Polyposis Coli (AAPC) and Peutz-Jeghers Syndrome.
There are some cancer syndromes with pancreatic cancer associated with them, such as familial melanoma, Peutz-Jeghers syndrome, and BRCA-2.