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5 Peripheral Quantitative Computed Tomography (pQCT) 4.
The advent of peripheral quantitative computed tomography (pQCT), a three-dimensional measurement technique, has revealed that BMD loss differs at trabecular bone sites of the distal and proximal epiphyses  and that bone loss at diaphyseal sites occurs as a result of cortical wall thinning, not by decline of BMD [13,20].
Peripheral quantitative computed tomography (pQCT) allows the noninvasive evaluation of bone strength parameters of long bones .