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Acronymfinder

What does PMD stand for?

PMD stands for Pelizaeus-Merzbacher Disease


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In a Phase I clinical trial in Pelizaeus-Merzbacher disease (PMD), a fatal myelination disorder in children, the Company has shown preliminary evidence of progressive and durable donor- derived myelination in all four patients transplanted with HuCNS-SC cells.
Two weeks after being surgically transplanted into either fetal or newborn rats with a congenital disease identical to the rare human myelin disorder Pelizaeus-Merzbacher disease, the laboratory-grown cells had developed into numerous myelin sheaths around nerve fibers previously without myelin.
Their afflicted sons - Vincent, 14, Russell, six, Nathan, four, and two- year-old Damian - all suffer from Pelizaeus-Merzbacher Disease, which is so rare that only 22 families in the country have been diagnosed as victims.
R Tina (September 2001) has a 2-year-old son with Pelizaeus-Merzbacher disease (a rare inherited disease of the central nervous system associated with progressive deterioration of the white matter of the brain) whose head sweats profusely at night, interrupting his sleep.
StemCells has also announced plans to initiate at the University of California, San Francisco (UCSF) Children's Hospital a Phase I trial of its HuCNS-SC cells in Pelizaeus-Merzbacher Disease (PMD), a fatal myelination disorder that primarily affects young children.