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Samples in periodicals archive:
Papillon-Lefevre syndrome was ruled out by a dermatologist with experience in this condition on the basis that our patient presented with no dermatological signs of this condition and had normal neutrophil function tests.
Differential diagnosis may include hypocalcified form of amelogenesis imperfecta, congenital erythropoietic porphyria, Kostmann's condition (conditions leading to early tooth loss), cyclic neutropenia, Chediak-Hegashi syndrome, histiocytosis X, Papillon-Lefevre syndrome, tetracycline discoloration and staining of the teeth, vitamin D-dependent and vitamin D-rickets.
The list includes diabetes, chronic or cyclical loss of white blood cells, Papillon-Lefevre syndrome, Down syndrome, scurvy, dentin dysplasia, regional odontodysplasia, Langerhans cell disease, leukemia, AIDS and hypophosphatasia.
Aim: The aim of this article is to present a review of the most current literature regarding the aetiology of the periodontal disease that occurs in patients with Papillon-Lefevre syndrome (PLS).