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Scientists found traces of parabens in 18 of 20 tissue samples in their study, entitled "Significance of the Detection of Esters of p-Hydroxybenzoic Acid (Parabens) in Human Breast Tumours," which Doctor Philippa Darbre and her colleagues at the British University of Reading published in the Journal of Applied Toxicology.
The concentration of such organic acids ranging from the highest to the lowest is as follows: ferulic acid > synapic acid > p-coumaric acid > p-hydroxybenzoic acid > vanilic acid > syringic acid.
Parabens are esters of p-hydroxybenzoic acid used as antimicrobial preservatives, especially against molds and yeast, in cosmetics, pharmaceuticals, and in food and beverage processing.
1989) isolated two phytoinhibitors, p-hydroxybenzoic acid and p-hydroxybenzaldehyde, from aqueous extracts of sudex (Sorghum-sudangrass hybrid) shoot tissue.
KEY WORDS: biomonitoring, exposure, human, NHANES, p-hydroxybenzoic acid esters, urine.
Until now, the only biomarker used for human paraben exposure was p-hydroxybenzoic acid in urine.
In animals, parabens are mostly hydrolyzed to p-hydroxybenzoic acid and excreted in the urine as conjugates.