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Capability of urinary components to enhance ornithine decarboxylase activity and promote urothelial tumorigenicity.
Polypeptide Growth Factors - Basic Fibroblast Growth Factor - Beta-TGF - Cachectin (TNT) - Calmodulin - ECFR - Nerve Growth Factor (NGF) - Epidermal Growth Factor (EGF) - Ornithine Decarboxylase - Transferrin - Transforming Growth Factor-Alpha 29.
It was positive for ornithine decarboxylase, gelatinase, reduction of nitrates to nitrites, tolerance to 6% NaCl, and assimilation of caprate and malate, but negative for citrate utilization, arginine dihydrolase, lysine decarboxylase, urease, indole production, assimilation of mannose, glucose, arabinose, mannitol, maltose, adipate, and acidification of glucose.
DMFO (alpha-difluoromethylornithine, also known as eflornithine) irreversibly inhibits ornithine decarboxylase, an enzyme unregulated in many tumors.
Due to their co-location with ornithine decarboxylase in the cytosol, arginase I can preferentially direct ornithine to the synthesis of polyamines, while arginase II can direct ornithine to the production of proline and glutamate, as both arginase II and ornithine aminotransferase are located in the mitochondria (Figure 5).
speciosa leaves (EHS) was evaluated in a battery of in vitro tests [inhibition of aromatase, NF-[kappa]B and ornithine decarboxylase (ODC), antioxidant response elements (ARE) induction and cell proliferation assays].
API 20E[R] strips also test for the presence of [beta]-galactosidase, arginine dihydrolase, lysine decarboxylase, ornithine decarboxylase, citrate utilization, [H.
The ornithine synthesized by arginase could also act through other pathways in the pancreatic islets, besides the production of polyamines, as it has been proven in isolated islets that ornithine has a positive effect on insulin secretion and that a-difluoromethylornithine, a specific inhibitor of ornithine decarboxylase, the enzyme that turns ornithine into putrescine, does not block its insulin secretagogue action .