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Samples in periodicals archive:
Today, there is clear evidence from in vivo and in vitro studies that glyburide does not cross the placenta in any appreciable quantity while metformin, another oral glucose-lowering agent, crosses the placenta freely.
Metformin served as the comparator in determining all-cause mortality risks for the other oral glucose-lowering agents in a multivariate analysis adjusted for age, gender, years of diabetes, cardiovascular medications, and socioeconomic status.
Patients in the study are given pioglitazone at the highest tolerated dose (up to 45 mg) or placebo, with other diabetes medications (non-TZD oral glucose-lowering agents with or without insulin) administered concomitantly.
More information is sorely needed about the possible effects of oral glucose-lowering agents during pregnancy.
Although some recent data suggested that metformin and sulfonylureas are probably not teratogenic, the use of any oral glucose-lowering agent still should be avoided during pregnancy and breast-feeding.
More information is sorely needed about the possible effects of oral glucose-lowering agents during pregnancy Although type 2 diabetes is a growing problem among women of childbearing age, there are virtually no prospective, randomized data about the safety of commonly used oral diabetes drugs on the developing fetus, said Dr.
While 72% of the patients were taking either oral glucose-lowering agents or insulin, 28% were on a statin or other LDL-lowering drug.