What does OR stand for?

In the DLBCL cohort, the objective response rate was 15 percent (one CR and five PRs) for enrolled patients and of the evaluable patients in this cohort, 60 percent experienced tumor reduction as assessed by CT scan.

The company said its experimental drug bavituximab, in combination with Sanofi-Aventis' chemotherapy drug Taxotere, prompted a 61 percent objective response rate in 46-patient midstage study.

The primary endpoint of the study is objective response rate assessed by independent review.

Anti-HER2 Antibody, Trastuzumab in Patients with Recurrent or Refractory Ovarian or Primary Peritoneal Carcinoma with Overexpression of HER2 Abstract & Commentary Synopsis: The clinical value of single-agent trastuzumab in recurrent ovarian cancer is limited by the low frequency of HER2 overexpression and low rate of objective response among patients with HER2 overexpression.

Among the findings were: * The estimated clinical benefit rate was 25%, consisting of patients with an objective response and/or sustained stable disease (non-progression for at least 77 days).

Among the findings were: * The estimated clinical benefit rate was 25%, consisting of patients with an objective response and/or sustained stable disease (non-progression for at least 77 days).

The primary endpoint of the study is objective response as measured over a 6 month period from start of treatment assessed by an Independent endpoints Review Committee (IRC) according to the standardized criteria for NHL.

ABSTRACT & COMMENTARY Synopsis: The clinical value of single-agent trastuzumab in recurrent ovarian cancer is limited by the low frequency of HER2 overexpression and low rate of objective response among patients with HER2 overexpression.