What does NPC stand for?

Papers address nuclear pore complex organization and nucleoporin functions, structural analysis of karyopherin-mediated nucleocytoplasmic transport, the translocation channel of the nuclear pore complex, nuclear export of ribosomes, nuclear-cytoplasmic tRNA trafficking, mRNA export as an integrative component of gene expression, import and export of UsnRNPs, transport of inner nuclear membrane proteins, nucleocytoplasmic transport of steroid hormone receptors, the role of the cytoskeleton in nucleocytoplasmic transport, and single substrate and transport receptor molecules at the nuclear pore complex.

A new classifier, called Nuc-PLoc, has been developed that can be exploited to recognize nuclear proteins among the following nine subnuclear locations: chromatin, heterochromatin, nuclear envelope, nuclear matrix, nuclear pore complex, nuclear speckle, nucleolus, nucleoplasm and nuclear promyelocytic leukemia (PML) body.

Actin entering the nucleus through the nuclear pore complex could be directly utilized for polymer formation, or enriched through interaction with the nuclear lamina, allowing regionalized regulation of actin concentration and polymer formation.

Our group has shown that huntingtin can dynamically travel between the cytoplasm and the nucleus, exporting the nucleus by a carboxy-terminal nuclear export signal (NES) that uses the exportin pathway of nuclear export across the nuclear pore complex (Xia et al.

The nuclear pore complex protein ALADIN is mislocalized in triple A syndrome.