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EYLEA has already been approved in Japan for the treatment of patients with neovascular age-related macular degeneration (wet AMD), macular edema secondary to central retinal vein occlusion (CRVO), and myopic choroidal neovascularization (myopic CNV).
Bayer HealthCare has received approval from the Ministry of Health, Labour and Welfare (MHLW) in Japan for EYLEA (aflibercept solution for injection) for the treatment of myopic choroidal neovascularization (myopic CNV).
Diseases and conditions covered include endogenous angiogenic inhibitors in diabetic retinopathy, corneal angiogenesis, polypoidal choroidal vasculopathy, myopic choroidal neovascularization, Eale's Disease, ocular tumorigenesis and the genetics of ocular vascular disease.
New data from the Phase 3 MYRROR trial of VEGF Trap-Eye (aflibercept solution for intravitreal injection) confirm the long-term success with VEGF Trap-Eye for the treatment of myopic choroidal neovascularization (mCNV).
](aflibercept) Injection from the Phase 3 MYRROR study in myopic choroidal neovascularization (mCNV).
This research across multiple retinal disease areas, including wet age-related macular degeneration (AMD), diabetic macular edema (DME), retinal vein occlusion (RVO) and myopic choroidal neovascularization (CNV), demonstrates that Lucentis with a wealth of real world long term experience is the pioneering anti-VEGF ocular treatment with its transformational efficacy, individualized treatment regimen, and well established long-term safety profile.
Eylea is also being studied for other indications, such as macular edema following branch retinal vein occlusion and myopic choroidal neovascularization.
Phase III trials are currently under way with VEGF Trap-Eye in the treatment of diabetic macular edema (DME) and myopic choroidal neovascularization (mCNV).