Introduction Multiple endocrine neoplasia type 1 (MEN-1) is defined as presence of any two tumors out of the following; parathyroid, neuroendocrine tumor (NECT) and pituitary neoplasia.
What does MEN stand for?
MEN stands for Multiple Endocrine Neoplasia
This definition appears very frequently and is found in the following Acronym Finder categories:
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See other definitions of MEN
We have 36 other meanings of MEN in our Acronym Attic
- McCallen (Amtrak station code; TX)
- Menu (File Name Extension)
- Metro Ethernet Network
- Middle East News
- Mikro Elektronik Nürnberg (Germany)
- Ministère de l'Education National (France)
- Ministère de l'éducation Nationale, de la Recherche et de la Technologie (French)
- Ministerstwo Edukacji Narodowej (Polish: Ministry of Education)
- Multi-Mode Equivalent Network
- Multiple Earth Neutral (electrical system used in New Zealand)
- Museum of Ethnography in Neuchâtel (Switzerland)
- Music Export Norway (est. 2000)
- Multiple Endocrine Neoplasia Type 2 Syndromes
- Multiple Endocrine Neoplasia Syndrome Type-2A
- Multiple Endocrine Neoplasia Syndrome Type 2B
- Multiple Endocrine Neoplasia Type I (aka Wermer's Syndrome)
- Multiple Endocrine Neoplasia Type II (endocrinology)
- Multiple Endocrine Neoplasia Type 1
- Multiple Endocrine Neoplasia Type 2
- Multiple Endocrine Neoplasia Type I
Samples in periodicals archive:
Both types of tumors are associated with conditions that are inherited in an autosomally dominant manner, such as: multiple endocrine neoplasia type 2 (MEN2),  which is due to a mutation in the RET  (ret proto-oncogene) protooncogene; von Hippel-Lindau disease (VHL), which is due to a mutation in the VHL (von Hippel-Lindau tumor suppressor) gene; neurofibromatosis type 1 (NF1), caused by mutation in the NF1 (neurofibromin 1) gene; and mutations in succinate dehydrogenase (SDH) subunits B, C, and D, which are encoded by the SDHB [succinate dehydrogenase complex, subunit B, iron sulfur (Ip)], SDHC (succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa), and SDHD (succinate dehydrogenase complex, subunit D, integral membrane protein) genes.
8) However, previously reported cases of a concomitant parathyroid adenoma and a leiomyoma occurred only in patients with multiple endocrine neoplasia type 1.
1,2) Pancreatic endocrine neoplasms are usually sporadic but may be part of hereditary syndromes mostly including multiple endocrine neoplasia type 1 (MEN-1) and, more rarely, von Hippel-Lindau (VHL) syndrome, neurofibromatosis type 1 (NF1), and tuberous sclerosis complex (TSC).
Quality of Life in Patients with Multiple Endocrine Neoplasia Types I.
Biochemical evaluation should include a 24-hour urine collection for norepinephrine, epinephrine, metanephrines, normetanephrines, dopamine, and VMA, or plasma metanephrines and normetanephrines, which is expensive, but more sensitive, especially in patients who may harbor occult diagnoses of familial syndromes, such as multiple endocrine neoplasia Type 2, Von Hippel Lindau or familial paragangliomas.
The association of cutaneous amyloidosis and multiple endocrine neoplasia type 2A (MEN 2A or Sipple syndrome--a rare autosomal dominant disease characterized by medullary thyroid carcinoma, pheochromocytoma, and primary hyperparathyroidism) has been reported (4).
In contrast, testing an individual with multiple endocrine neoplasia type-2 (MEN-2) for the RET proto-oncogene can avoid medullary carcinoma if the individual is positive and undergoes a prophylactic thyroidectomy.