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What does MEN stand for?

MEN stands for Multiple Endocrine Neoplasia

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Both types of tumors are associated with conditions that are inherited in an autosomally dominant manner, such as: multiple endocrine neoplasia type 2 (MEN2), [2] which is due to a mutation in the RET [3] (ret proto-oncogene) protooncogene; von Hippel-Lindau disease (VHL), which is due to a mutation in the VHL (von Hippel-Lindau tumor suppressor) gene; neurofibromatosis type 1 (NF1), caused by mutation in the NF1 (neurofibromin 1) gene; and mutations in succinate dehydrogenase (SDH) subunits B, C, and D, which are encoded by the SDHB [succinate dehydrogenase complex, subunit B, iron sulfur (Ip)], SDHC (succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa), and SDHD (succinate dehydrogenase complex, subunit D, integral membrane protein) genes.
1,2) Pancreatic endocrine neoplasms are usually sporadic but may be part of hereditary syndromes mostly including multiple endocrine neoplasia type 1 (MEN-1) and, more rarely, von Hippel-Lindau (VHL) syndrome, neurofibromatosis type 1 (NF1), and tuberous sclerosis complex (TSC).
Biochemical evaluation should include a 24-hour urine collection for norepinephrine, epinephrine, metanephrines, normetanephrines, dopamine, and VMA, or plasma metanephrines and normetanephrines, which is expensive, but more sensitive, especially in patients who may harbor occult diagnoses of familial syndromes, such as multiple endocrine neoplasia Type 2, Von Hippel Lindau or familial paragangliomas.
The association of cutaneous amyloidosis and multiple endocrine neoplasia type 2A (MEN 2A or Sipple syndrome--a rare autosomal dominant disease characterized by medullary thyroid carcinoma, pheochromocytoma, and primary hyperparathyroidism) has been reported (4).