The resultant metabolite is normally inactive, although there are exceptions to this, such as morphine-6-glucuronide, which has stronger analgesic effect than morphine itself.
What does M6G stand for?
M6G stands for Morphine-6-Glucuronide (molecule)
This definition appears frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of M6G
We have 3 other meanings of M6G in our Acronym Attic
- Mean of 1950 (coordinate system)
- Meperidine 50 Milligrams
- Tracked Vehicle SICPS Shelter
- Mark 5 Army Nerf Gun Corps
- Method 5 Acid Train
- Mode 5 Level 2
- Movimento 5 Stelle (Italian: 5 Stars Movement; political party)
- Major Sixth (music)
- Métropole 6 (French TV Network)
- Minor Sixth (music)
Samples in periodicals archive:
Morphine is commonly avoided in such patients because of the risk of accumulation of metabolites, in particular morphine-6-glucuronide, which is also excreted by the kidneys and is a more potent mu-opioid agonist than morphine (2).
Influence of renal failure on the disposition of morphine, morphine-3-glucuronide and morphine-6-glucuronide in sheep during intravenous infusion with morphine.
Stability of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in fresh blood and plasma and postmortem blood samples.
Comparison of the hydrolysis rates of morphine-3-glucuronide and morphine-6-glucuronide with acid and 0-glucuronidase.
Morphine-6-glucuronide but not morphine 3-glucuronide is an analgesically active morphine metabolite (7).
Morphine-6-glucuronide is considered to be even more active than the parent drug (28).