What does MEGX stand for?

Monoethylglycinexylidide (plasma component)

This definition appears very rarely and is found in the following Acronym Finder categories:

Science, medicine, engineering, etc.

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Samples in periodicals archive:

Blood was drawn to evaluate levels of lidocaine and monoethylglycinexylidide (MEGX) metabolites prior to application of the occluded cream at 1 hour, 2 hours, 6 hours, and 24 hours post-application.

Safety of occluded 4% liposomal lidocaine cream

The test is based on the conversion of lidocaine to its deethylated metabolite monoethylglycinexylidide (MEGX), primarily through the hepatic cytochrome P450 system.

Rapid and sensitive liquid chromatography-tandem mass spectrometry ...

Monoethylglycinexylidide (MEGX), the primary metabolite of lidocaine, is produced via oxidative N-deethylation catalyzed by cytochrome P450 (CYP) 3A4 (1).

Effects of chronic renal failure and hemodialysis on the ...

Lidocaine, a commonly used local anesthetic and antiarrythmic agent, is eliminated from the body primarily by hepatic metabolism to monoethylglycinexylidide (MEGX) [4].

Assessment of monoethylglycinexylidide as measure of liver function ...

Monoethylglycinexylidide formation kinetics: a novel approach to assessment of liver function.

Xenobiotic-induced hepatotoxicity: mechanisms of liver injury and ...

Specifically, the kinetics of the lidocaine metabolite monoethylglycinexylidide (MEGX) can be used to assess hepatocyte injury [22-24].

Assessment of liver function: pre- and peritransplant evaluation

The hepatic conversion of lidocaine to its metabolite monoethylglycinexylidide (MEGX) is catalyzed by the cytochrome P450 enzyme CYP3A4 in humans.

Determination of MEGX by HPLC with fluorescence detection

For certain compounds such as propoxyphene and its metabolites, diphenhydramine, promethazine, and lidocaine and its major metabolite monoethylglycinexylidide, Remedi scored remarkably high.

Automated liquid-chromatographic analyzer used for toxicology ...