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What does MCP-1 stand for?

MCP-1 stands for Monocyte Chemoattractant Protein-1


This definition appears very frequently and is found in the following Acronym Finder categories:

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Samples in periodicals archive:

The expression of immunomodulatory membrane molecules such as inter-cellular adhesion molecule-1 (ICAM-1) by Western blot analysis, and the release of chemokines such as monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) through ELISA kits, were determined.
The main function of IL-17-secreting T cells is to mediate inflammation, by stimulating production of inflammatory cytokines, such as TNF-alpha, IL-1beta and IL-6, and inflammatory chemokines, including CXCL-6, CXCL-7, CXCL-8, IL-8 and monocyte chemoattractant protein-1 (MCP-1), and metalloproteinases that promote the recruitment of neutrophils and macrophages (recruited by Thl cells) resulting in inflammation and tissue pathology (Fig.
Other topics include intrathecal upregulation of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis, serum levels of interleukin-16 in lymphoid neoplastic diseases, and syndecans as modulators of chemokine function.
With respect to inflammatory diseases of the kidney, leukocyte infiltration is mediated by proinflammatory chemokines, (19-23) and the chemokine monocyte chemoattractant protein-1 (MCP-1) has been shown to be pathogenic for kidney injury in murine lupus nephritis, and significantly associated with human SLE nephritis.