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Samples in periodicals archive:
1% mark, or 3 log decrease in BCR-ABL transcript, is defined as the Major Molecular Response or MMR.
At the ENESTnd six-year follow up, we still see consistent evidence of deeper molecular response and fewer progressions to advanced disease in patients taking Tasigna compared to those on Gleevec," said Giuseppe Saglio, MD, ENEST studies investigator, Professor of Internal Medicine and Haematology and Director of the Department of Molecular Medicine and Targeted Therapy, San Luigi University Hospital at the University of Turin, Orbassano, Italy.
5 years, I maintain in culture several isoclonal lines of Daphnia (under different conditions) to understand the mechanisms of molecular responses to environmental challenges.
] (imatinib) 400 mg[as defined by time to achieve Complete Cytogenic Response (CCYR) or Major Molecular Response (MMR)].
The presence of this complex activates a molecular response that disables the parasite.
Molecular responses to xenoestorgens: mechanistic insights from toxicogenomics.
Tracking cellular and molecular responses holds the most promise for filling this need, he says.
There are three important elements involved in this work: quantifying the response to adverse environmental stress conditions; establishing the molecular response at the cellular level when cells are exposed to adverse environmental stress conditions; and developing advanced predictive models and quantitative risk assessments.