We focus on two proteins which are targets for cancer therapy: p38 mitogen-activated protein kinase and Abl.
What does MAPK stand for?
MAPK stands for Mitogen-Activated Protein Kinase
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of MAPK
We have 12 other meanings of MAPK in our Acronym Attic
- Mandate for Public Interest Law (Canada)
- Market Participant and Investor (SEBI unique identification number)
- Maritime and Port Information System (Cartagena, Colombia)
- Map Based Interaction in Social Networks
- Montana Association of Private Investigators & Security Operators
- Manchester Anomalous Phenomena Investigation Team
- Mission Area to Programming Integration Tool
- Modelling Approach That Is Participatory Iterative for Understanding
- Manhattan Alliance for Peace and Justice (Manhattan, KS)
- Microtubule-Associated Protein Kinase
- Mitogen-Activated Protein Kinases/Extracellular Signal-Regulated Kinases
- Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase 2
- Mitogen Activated Protein Kinase 1
- Mitogen Activated Protein Kinase 13
- Mitogen Activated Protein Kinase 8
- Mitogen Activated Protein Kinase 9
- Mitogen Activated Protein Kinase Activated Protein Kinase
- Mitogen-Activated Protein Kinase-Activated Protein Kinase
- Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (gene)
- Mitogen-Activated Protein Kinase-Activated Protein Kinase 3
Samples in periodicals archive:
This is also true for the signal transduction pathways, for example cyclooxygenase 2 (Cox-2), HER2/neu, mitogen-activated protein kinase (MAPK), and PI3K/Akt.
ERK 1/2, which are also known as classical mitogen-activated protein kinases (MAPKs), were found to be increased in the RPE of human eyes with GA and shown to be key mediators of RPE cell death.
The MAPKs that have been shown to play pivotal roles in proinflammatory signaling are extracellular signal-regulated kinase (ERK), p38 mitogen-activated protein kinase (p38 MAPK) and c-Jun NH2-terminal kinase (JNK) (Davis, 1994).
Among their topics are myth and science regarding laser and light therapy for acne, emerging trends in the diagnosis and management of atopic dermatitis, which side mitogen-activated protein kinases and their inhibitors are on in the fight against psoriasis, dendritic cell immunotherapy for treating malignant melanoma, malignant melanoma in ethnic skin, a novel transdermal drug delivery system mediated by arginine-rich intracellular delivery peptides, and onychomysosis caused by non-dermatophytic filamentous fungi.
HER2 overexpression results in activation of multiple intracellular signalling pathways, including the phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) cascades which act to modulate cellular proliferative and survival responses, and tumours overexpressing HER2 have been found to be more aggressive in comparison with tumours that do not.
The mitogen-activated protein kinase (MAPK) superfamily are proline-directed protein kinases that mediate the effects of numerous extracellular stimuli on a wide array of biologic processes, such as cellular proliferation, differentiation, and death.
Interpretation & conclusions: The ex vivo expansion of human limbal epithelial progenitor cells on intact HAM was mediated by PI3K/Akt/FKHRLI pathway, which is known to govern cell survival, and the mitogen-activated protein kinase (MAPK) pathway, known to control the cell mitosis.