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Women appear to have the same minimum alveolar concentration as men: a retrospective study.
32%) was within the range of the minimum alveolar concentration reported in mammals.
Intraoperative age-adjusted minimum alveolar concentration (MAC) was determined using an established nomogram (18).
A representative patient from this group was a 32-year-old, 104 kg woman who received a total dose of rocuronium of 100 mg over a 150 minute operative procedure during which 1 minimum alveolar concentration isoflurane had been used as part of a balanced anaesthetic.
A] is related to the clinical end-points of immobility and hypnosis as described by minimum alveolar concentration (MAC) and MACawake 'concepts', respectively (2,3).
After a period of time in which the partial pressure of sevoflurane in the brain would have equilibrated with the alveolar partial pressure (6,7), the patient showed clinical signs of adequate anaesthesia and had an end-tidal sevoflurane concentration of more than 1 minimum alveolar concentration, but the entropy monitor still indicated an awake state.
Opioid agents significantly reduce the minimum alveolar concentration of potent inhaled anaesthetics required to facilitate intubation and improve overall intubating conditions during sevoflurane anaesthesia (5,6).
Several studies have shown a decreased maternal minimum alveolar concentration (MAC) for inhalational agents during pregnancy (1-3).