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The initial dose is 70% of the minimal erythemal dose, with dose increments of 40% every other treatment from treatments one to four, dose increments of 30% every other treatment from treatments four to eight, and dose increments of 20% every other treatment thereafter.
Day 1 -- determination of Minimal Erythemal Dose (MED).
25 times the minimal erythemal dose of radiation from a solar simulator, UV-induced erythema was significantly decreased in the high flavanol group by 15% and 25% after six and 12 weeks of treatment, respectively, whereas no change occurred in the low flavanol group.