Cortisol binds to mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs), and feedback onto the PVN is excitatory or inhibitory depending on the location and type of receptor.
What does MR stand for?
MR stands for Mineralocorticoid Receptor
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of MR
We have 107 other meanings of MR in our Acronym Attic
- Middle Reliever (baseball)
- Midland Railway (UK)
- Midship Runabout (Toyota)
- Milano Red (Honda paint color)
- Militaires du Rang (Canada)
- Military Region
- Milk Replacer
- Mind Rape
Samples in periodicals archive:
When obese "salt-sensitive" rats were fed a high-salt diet, the team found that Rac1 activated the mineralocorticoid receptor (MR) on the rats' kidney cells.
Eplerenone acts as a competitive and selective aldosterone blocker (SAB) at the mineralocorticoid receptor sites in various tissues throughout the body.
Although this novel finding is "encouraging" and a confirmatory large randomized controlled clinical trial is likely, the study results were only partly positive; after all, the hypothesis was that stimulating the mineralocorticoid receptor would also boost the overall response rate--and it didn't happen, Dr.
13) High-dose estrogens may induce sodium retention and volume expansion through an interaction with mineralocorticoid receptors or effects on 11 [beta]-HSD activity.
]-dependent dehydrogenase of glucocorticoids, thus "protecting" the mineralocorticoid receptor against cortisol.
Both of the studies emphasize that spironolactone influences PAI-I concentrations through mineralocorticoid receptor antagonism rather than through changes in potassium.
Evidence that high dose cortisolinduced Na+ retention in man is not mediated by the mineralocorticoid receptor.