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Tools to measure the functional assessment of dyspnea have been developed, such as the Baseline Dyspnea Scale, (17) Medical Research Council Dyspnea scale, (18) Modified Borg Scale, (19) Modified Shuttle Walking test, (20) Oxygen Cost Diagram, (21) Pulmonary Functional Status and Dyspnea Questionnaire, (22) and the UCSD Shortness of Breath Questionnaire.
Methods: We studied 205 patients with COPD (mean [[+ or -]SD] FEV(1), 43 [+ or -] 15% predicted), and recorded the body mass index, FEV1 percent predicted, modified Medical Research Council dyspnea scale, 6-min walk distance, and the BODE index at baseline, during the exacerbation, and at 6, 12, and 24 months following the first episode, and documented all exacerbations for 2 years after the first acute exacerbation.