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What does LES stand for?

LES stands for Lower East Side (Manhattan)

This definition appears very frequently

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Other Resources:
We have 198 other meanings of LES in our Acronym Attic

Samples in periodicals archive:

LUIS SOLER GREW UP IN ALPHABET CITY, TOUGH turf on New York City's Lower East Side.
JSA* This slim, delightful volume of the stories of four immigrant families who settled in a dark tenement building on New York's Lower East Side humanizes the struggles and triumphs of those families while reflecting on the shared experiences of all immigrants who come to America seeking a new life.