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Samples in periodicals archive:
From these patients, the researchers looked for individuals who were new users of asthma controller medications, including inhaled corticosteroids, long-acting beta-agonists or leukotriene modifiers, or IACs, and who had continuous enrollment in the IMS system for at least six months prior to having the control medication dispensed.
In 14 chapters, respiratory specialists from Europe, North America, and Australia explain the specific mechanisms of therapies like glucocorticoids, inhaled corticosteroids, long-acting beta-agonists, combination therapy, anti-infective treatments, phosphodiesterase inhibitors, biological therapies in development, and others; how the components affect disease processes; and how the drugs interact.
Despite this negative finding, "our [results] suggest that there is little difference in real-world effectiveness between an LTRA and an inhaled glucocorticoid as first-line controller therapy and between an LTRA and a long-acting beta-agonist as an add-on to an inhaled glucocorticoid," they said.
A new study has found the addition of long-acting beta-agonist therapy to be the most effective of three step-up, or supplemental, treatments for children whose asthma is not well controlled on low doses of inhaled corticosteroids alone.
Fluticasone propionate/salmeterol (Advair) is a combination product of the corticosteroid fluticasone with the long-acting beta-agonist bronchodilator salmeterol.
Long-acting beta-agonists and inhaled corticosteroids have been used to treat chronic obstructive airways disease (COPD) for some time.
Until there is better evidence, combined treatment with an inhaled steroid and a long-acting beta-agonist should probably be reserved for people with severe disease.
AstraZeneca are the manufacturers of Symbicort(R), a combination of the inhaled corticosteroid budesonide and rapid- and long-acting beta-agonist formoterol, which is indicated for the treatment of COPD and asthma References: 1) Primary Care Physicians' Perception and Practice in Management of COPD Patients (results from the Time to Live report), scheduled for presentation at ATS, May 21, 2006 2) http://www.