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8), as seen in a R-P-R (resection--plication--release) operation described by Swistel (55), the post-surgical study will show: 1) a dramatic thinning of the septum, with widening of the left ventricular outflow tract to a width similar to that in the normal subjects, 2) resolution of systolic anterior motion and the left ventricular outflow tract gradient, 3) marked reduction or abolition of mitral regurgitation, 4) decreased anterior mitral leaflet length and 5) more posterior mitral leaflet coaptation point (5, 53, 55).
Hypertrophic cardiomyopathy is invariably associated with left ventricular diastolic dysfunction due to impaired relaxation and reduced compliance, and it may be associated with dynamic left ventricular outflow tract gradient and mitral regurgitation (3).
Hypertrophic cardiomyopathy: is a left ventricular outflow tract gradient a major prognostic determinant?