What does JAK stand for?

Janus Kinase (aka Just Another Kinase)

This definition appears very rarely and is found in the following Acronym Finder categories:

Science, medicine, engineering, etc.

Other Resources:

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Japan Agricultural Journalists' Association Justice for Aquino Justice for All Just Another Jabber Client Jonathan Alder Junior High School (Ohio) January, April, July and October (option cycle) Japan-Australia Jazz Orchestra Jewish Alliance for Justice and Peace (Chicago, IL) Jessie and James Romance Novels (Pokemon fan fiction) J. Ashburn Jr. Youth Center (Columbus, OH) Jakovlev (Soviet aircraft designer)		Jayne Ann Krentz (author; aka Amanda Quick and Jayne Castle) Jazakom Allaho Khairan (Arabic: May Allah Reward You; Thank You) Journalists Association of Korea (South Korea) Just Another Kinase (aka Janus Kinase) Janus Kinase and Signal Transducer and Activator of Transcription (cytology) Janus Kinase/Signal Transducer and Activator of Transcription Janus-Activated Kinase 1 Janus Family Kinase-2 (endocrinology) Janus-Activated Kinase 2 Just Another Kinase 2 (now Janus-Activated Kinase 2; biochemistry)

Samples in periodicals archive:

There was a similar effect with Janus Kinase 2 (Jak2), the main intermediary of EpoR signaling.

Anemia drugs may speed growth of cancer

The up-regulation of eNOS at the transcriptional level has recently been found to be mediated by an extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway, namely, phosphatidylinositol-3 kinase [gamma] (PI-3K[gamma]) [right arrow] Janus kinase 2 (Jak2) [right arrow] mitogen-activated protein kinase--extracellular signal-regulated kinase kinase 1 [right arrow] ERK1/2 [right arrow] promoter selective transcription factor 1 (sp1), which binds to its cognate site on the eNOS promoter-enhancer region via the action of protein phosphatase 2A (Cieslik et al.

Downregulation of human endothelial nitric oxide synthase promoter ...

Taken by mouth, CP-690,550 specifically blocks janus kinase 3 (JAK 3), an enzyme that regulates the activation and reproduction of white blood cells-immune cells that attack transplanted organs or, in autoimmune disease, the body's own healthy tissue.

Experimental immunosuppressant shows promise of preventing organ ...

Below is a summary of recent developments for our most advanced product candidates: Janus Kinase (JAK) Inhibitor Program INCB18424: (oral formulation) Myelofibrosis, Polycythemia Vera and Essential Thrombocythemia * Agreement reached with the U.

Incyte Reports Second Quarter 2009 Financial Results and Provides ...

Below is a summary of recent developments for our most advanced product candidates: Janus Kinase (JAK) Inhibitor Program INCB18424: (oral formulation) Myelofibrosis (MF), Polycythemia Vera (PV) and Essential Thrombocythemia (ET) * Resubmitted the Special Protocol Assessment to the U.

Incyte Reports First Quarter 2009 Financial Results and Provides ...

Janus Kinase (JAK) Inhibitor Program INCB18424: Myelofibrosis (MF), Polycythemia Vera (PV) and Essential Thrombocythemia (ET) (oral formulation) * Submitted a Special Protocol Assessment for approval in MF in December.

Incyte Reports Fourth Quarter and Year-End 2008 Financial Results; ...

JAK3 Inhibitor for Immune-Mediated Inflammatory Diseases * Vertex has completed a Phase 1 clinical trial of VX-509, a novel Janus kinase 3 (JAK3) inhibitor.

Vertex Pharmaceuticals Provides HCV and Cystic Fibrosis Update and ...

These programs include: * Janus kinase (JAK) inhibitor program for: - myelofibrosis (MF), - polycythemia vera (PV) & essential thrombocythemia (ET), - rheumatoid arthritis (RA) and - psoriasis * 11beta-HSD1 (HSD1) inhibitor program for type 2 diabetes * Sheddase inhibitor program for breast cancer Paul Friedman, M.

Incyte to Announce 2009 Objectives at JPMorgan Healthcare Conference; ...