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Agency : Istituto di Ricovero e Cura a Carattere Scientifico CROB
The study was performed according to guidelines of the institutional review board of the Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico Policlinico, San Matteo, Pavia, Italy, on the use of biological specimens for scientific purposes in keeping with Italian law (Article 13 D.
 Unita Operativa Complessa di Pediatria e Genetica Medica Istituto di Ricovero e Cura a Carattere Scientifico Oasi Maria Santissima Troina, Italy