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In addition, intranuclear inclusion bodies in cells of brains, peripherical nerves, tongues, and adrenal glands were observed.
Signs of the classic HSV cytopathic effect included the presence of intracellular proteinaceous fluid, ballooning degeneration of epithelial cells, and acantholysis (figure 2, A) as well as intranuclear inclusion bodies and a ground-glass appearance of some nuclei (figure 2, B).
In at least 2 studies, histologic pictures of celiac ganglia undoubtedly show intranuclear inclusion bodies, which strongly resemble the intranuclear inclusion bodies known from BD (2,18).
Postmortem examination showed nonsuppurative meningoencephalitis with neuronal and glial intranuclear inclusion bodies (Figure 1, panel A).
Histologically, the female falcons had mild necrotizing hepatitis with numerous intranuclear inclusion bodies and necrotizing splenitis with rare inclusion bodies.
A nonpurulent encephalitis with syncitial cells and intranuclear inclusion bodies, intracytoplasmic inclusion bodies, or both, were detected in 6 whales from which neurologic tissues were analyzed microscopically.
Intracytoplasmic and intranuclear inclusion bodies were seen in glossal epithelium.