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There are two staging systems for myeloma, the international staging system and the Durie-Salmon staging system.
The tool is conveniently separated into specific topic areas for quick information retrieval and covers the most common clinical features of multiple myeloma at presentation; recommended laboratory tests for diagnosis, prognosis and risk-stratification, including the roles of the serum free light chain assay, definitions of myeloma and related monoclonal gammopathies; a basic diagnostic algorithm; International Staging System and the International Myeloma Working Group Uniform Response Criteria among other features.
The case was regarded as stage IIIB according to prognostic Dude Salmon staging system and stage III according to the International Staging System (ISS) for MM (18), (19).
Use of the International Staging System (ISS) is also new to the guidelines.
The new International Staging System (ISS) provides a simple prognostic factor alternative to the Durie and Salmon clinical staging system used for more than 25 years.