Understanding the internal dose is essential to determine adverse effects on health, the researchers said.
What does Dint stand for?
Dint stands for Internal Dose
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Samples in periodicals archive:
In a longitudinal cohort study of nonsmoking African-American and Dominican women in New York City (the Northern Manhattan Mothers and Newborns Study), the authors measured PAH exposure during pregnancy using personal air monitors and quantified benzo[a]pyrene DNA adducts and genomic DNA methylation in cord blood DNA among 164 participants, and they assessed PAH internal dose using prenatal urinary metabolites in a subset of the women (n = 87).
Findings are reported on toxicity and internal dose, risk assessment, epidemiology and surveillance, engineering controls and personal protective equipment, measurement methods, exposure assessment, fire and explosion safety, recommendations and guidance, communications and education, and applications.
The latest radiation equipment is more portable, allowing doctors to deliver an internal dose during surgery to remove cancerous tissue.
The system uses physiologically based pharmacokinetic, or PBPK, mathematical models to translate exposure levels into the amount of internal dose received and the resulting health risk.
Radiation dose estimates were calculated using Organ Level INternal Dose Assessment EXponential Modeling (OLINDA/EXM).
Yet the ever-increasing data from human biomonitoring and epidemiological studies suggests otherwise: Low internal doses of endocrine disruptors found in typical human populations have been linked to obesity (Carwile and Michels 2011), infertility (Meeker and Stapleton 2010), neurobehavioral disorders (Swan et al.
The risk implications of free BPA detections need to be explored based upon dose-response assessment and suitable physiologically based pharmacokinetic (PBPK) modeling that can relate internal dose of free BPA to adverse effect.