What does IRS stand for?

Insulin Receptor Substrate

This definition appears very rarely and is found in the following Acronym Finder categories:

Science, medicine, engineering, etc.

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Samples in periodicals archive:

This appeared to influence a gene called insulin receptor substrate 1, or IRS1.

GENE HOPE FOR 2m DIABETES SUFFERERS; DNA link to type 2 illness holds ...

The novel gene, called Insulin Receptor Substrate 1 (IRS1), affects how the body responds to insulin already in the bloodstream.

New gene that causes insulin resistance in diabetics identified

This binding initiates a series of phosphorylation reactions that lead to the phosphorylation of several signaling intermediates on tyrosine residues, including the critical insulin receptor substrate proteins (such as IRS1 and IRS2).

Skeletal muscle insulin resistance: roles of fatty acid metabolism ...

GS-101 is an antisense oligonucleotide that acts by blocking the production of insulin receptor substrate 1 (IRS-1), a protein required for the formation and growth of new blood vessels.

Gene Signal Announces Publication of Phase I Data Highlighting Safety ...

Yet investigators who have engineered mice to lack a single gene--the one that encodes a protein called insulin receptor substrate 2 (IRS-2)--have found to their surprise that the animals display both of the main characteristics of type 2 diabetes.

Diabetic mice cast suspicion on protein

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein.

Pharmacologic management of hyperglycemia in diabetes mellitus: ...

The majority of the genes with increased expression were involved in insulin signal transduction pathway including insulin, insulin receptor, insulin receptor substrate, PDX1, glucagon, glucagon receptor, GLP-1 receptor, neuroD and Glut4.

Opexa Therapeutics Presents Monocyte-Derived Islet Cell Research at ...

The Joslin team studied "knockout" cell lines of brown preadipocytes that lacked insulin receptor substrates (IRS) numbered 1 through 4, which are the first steps in insulin signaling inside the cell.

Joslin Diabetes Center Scientists Find 'Brown Fat Cells' Hold Clues ...