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Washington, Jan 26 (ANI): Scientists have discovered two functional variants in the inosine triphosphatase (ITPA) gene that protect patients with hepatitis C virus (HCV) against anemia brought on by antiviral treatment.
Association of inosine triphosphatase 94C>A and thiopurine Smethyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study.
Previous studies had recognised the genetic variants as the cause of a deficiency in the production of an enzyme, inosine triphosphatase.