eIF4E is an attractive cancer therapeutic target because every function necessary for cancer growth and metastasis is influenced or mediated by a gene product that is regulated by this translation initiation factor.
What does IF stand for?
IF stands for Initiation Factor
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of IF
We have 26 other meanings of IF in our Acronym Attic
- Induction Furnace (metal melting)
- Industrial Facilities
- Industrial Fund
- Infield (baseball/softball)
- Information Directorate (at AFRL)
- Information Flow
- Ingenico Fortronic Ltd
Samples in periodicals archive:
Washington, August 21 ( ANI ): Researchers have discovered the way the protein, eukaryotic initiation factor 4E (eIF4E), acts upon cancer-promoting messenger RNA molecules.
We have identified a small molecule, guanabenz, which binds to a regulatory subunit of protein phosphatase 1, PPP1R15A/GADD34, selectively disrupting the stress-induced dephosphorylation of the alpha subunit of translation initiation factor 2 (eIF2 alpha).
We were surprised to find yet another translation initiation factor that has a profound effect on the proliferation of cancerous cells," said Armen Parsyan, a postdoctoral fellow, Department of Biochemistry.
subunit, one is a sugar beet dihydroorotase, one is a sugar beet translation initiation factor 1A and two others are of a unknown protein type.
Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor.
Selective stimulation of translation of leaderless mRNA by initiation factor 2: evolutionary implications for translation.
The social initiation factor (coming in contact with others performing the act).