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56,61,62) IDIOPATHIC PULMONARY HEMOSIDEROSIS Idiopathic pulmonary hemosiderosis (IPH) is a rare disease characterized by heavy lungs with aggregates of hemosiderin-laden macrophages due to recurrent diffuse alveolar hemorrhage in the absence of vasculitis or capillaritis and by eventual interstitial fibrosis (Figure 6).
Long-term clinical course of patients with idiopathic pulmonary hemosiderosis (1979 -1994): prolonged survival with low-dose corticosteroid therapy.
1-6) Travis et al (7) described 34 cases of diffuse pulmonary hemorrhage, reporting 43% of the cases caused by vasculitis, 13% caused by anti-basement membrane antibodies, 13% caused by idiopathic pulmonary hemosiderosis, 18% caused by pulmonary renal syndrome, and 13% caused by SLE or rheumatoid arthritis.