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Specifically the group, which is a practice of over 140 physicians and 40 non-physician clinicians who serve more than 350,000 patients, has recommended that Digene's advanced Hybrid Capture 2 technology be used in all its ASCUS patients to detect high- risk HPV (human papillomavirus), the cause of essentially all cervical cancer.
The investigators identified 1001 patients, aged 30 to 45 years, with a cytologically normal result following image-directed screening with the ThinPrep Imaging System, which were then tested for HR HPV using the Hybrid Capture 2 (hc2) method.
The results concluded that within a population "enriched" with a greater number of abnormal samples than a routine population, In-Cell HPV demonstrated higher sensitivity than Hybrid Capture 2 (83.