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What does HPBMC stand for?

HPBMC stands for Human Peripheral Blood Mononuclear Cell

This definition appears rarely and is found in the following Acronym Finder categories:

  • Science, medicine, engineering, etc.

Samples in periodicals archive:

Recently, a novel VPAC1 isoform was identified in human peripheral blood mononuclear cells (PBMC) that lacks exons 10-12 to form a 5TM receptor that lacks Gas coupling, but elicits significant tyrosine phosphorylation when treated with exogenous ligand in ectopically overexpressed CHO cells.
PPL-240(TM) -- photoprotective antioxidant Findings from Polypodium leucotomos extract, PPL-240, prevents solar-induced DNA damage in human peripheral blood mononuclear cells were presented April 6 (poster number: A414) and analyzed the effect of PPL-240 on the cellular damage of human peripheral blood mononuclear cells (PBMC) induced by solar radiation.
Two of the posters present information on Avalon's biomarker program for the company's lead clinical candidate AVN944: -- The first poster, part of a collaboration with scientists from Vertex Pharmaceuticals Incorporated, is a description of Avalon's biomarker discovery process where AvalonRx(R) is used across a panel of cancer cell lines and normal human peripheral blood mononuclear cells (PBMC's) to identify biomarkers of response as well as markers for use in identifying patient populations that may respond to therapy.
The accepted abstracts include an oral presentation of interim results from a Phase 1 clinical trial which evaluated IMO-2125 in null-responder HCV patients and a poster presentation of gene expression profiles in human peripheral blood mononuclear cells (PBMCs) stimulated with IMO-2125.
Abstract 1593: "IMO-2125, a TLR9 agonist, induces Th-1 type cytokines and interferons with potent anti-HCV activity in human peripheral blood mononuclear cells (PBMCs) and plasmacytoid dendritic cells (pDCs)" In this study, IMO-2125 induction of cytokines was evaluated in human peripheral blood mononuclear cells (hPBMCs) and plasmacytoid dendritic cells (pDCs).
Potency studies: independent studies, performed at Walter Reed Army Medical Facility, on another virus (HIV) on a blind basis have shown Alferon N to be up to 100-fold more effective than equal concentrations of two different recombinant IFNs for inhibition of virus replication in primary human peripheral blood mononuclear cells.