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Amgen , the world's largest biotechnology company, today announced data from a Phase 3 study showing that Palifermin, Amgen's proprietary recombinant human keratinocyte growth factor (rHuKGF) molecule, significantly reduced the duration and incidence of severe oral mucositis in patients with hematologic malignancies undergoing high-dose chemotherapy and radiotherapy and total body irradiation followed by hematopoietic stem cell support compared to placebo.
Associated Press Amgen cites role of growth factor THOUSAND OAKS - Pharmaceutical developer Amgen reported that recombinant human keratinocyte growth factor, or KGF, could reduce the duration of the painful condition known as oral mucositis.
About Kepivance Kepivance, a recombinant human keratinocyte growth factor, reduces the incidence and duration of severe oral mucositis by helping to protect existing epithelial cells that line the mouth and throat from the damage caused by chemotherapy and radiation, and stimulating the growth and development of new epithelial cells to build up the mucosal barrier.
for MONDAY (May 14) NOTE TO EDITORS: Multimedia Assets Available With This Story Include Logos, Text News Releases --(BUSINESS WIRE) Amgen (Nasdaq:AMGN) reported that data from two phase 2 clinical trials presented at the 37th annual meeting of the American Society of Clinical Oncology (ASCO) suggest that treatment with the investigational intravenous (IV) agent recombinant human keratinocyte growth factor (rHuKGF, also known as KGF) may reduce the duration of severe oral mucositis in cancer patients receiving chemo/radiotherapy.