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What does HGSIL stand for?

HGSIL stands for High-grade Squamous Intraepithelial Lesion (oncology, gynecology)

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Samples in periodicals archive:

The rate of low-grade squamous intraepithelial lesions (LSILs) with HPV-16/18 was 68% lower than in the control group, and the rate of high-grade squamous intraepithelial lesions (HSILs) with HPV-16/18 was 56% lower than in the control group, he said at the meeting.
The most recent classification is the Bethesda system, which divides the results of the morphologic interpretation into four main groups: 1) Cervical specimens negative for intra-epithelial lesions or malignancies (NILM) - cases with morphological interpretation within normal limits 2) Atypical Squamous Cells of Undetermined Significance (ASC-US) - cases with no definitive cellular abnormality but enough suspicion to keep the case from being considered "normal" (this is an ambiguous category) 3) Low-grade Squamous Intraepithelial Lesion (LSIL) 4) High-grade Squamous Intraepithelial Lesion (HSIL) Broadly speaking LSIL corresponds to mild to moderate pre-cancerous disease and HSIL corresponds to high-grade pre-cancerous disease.
The initial test is composed of 10 slides including at least one slide from each of the 4 categories: unsatisfactory (Category A), negative (Category B), low-grade squamous intraepithelial lesion (LSIL) (Category C), and high-grade squamous intraepithelial lesion and carcinoma (HSIL+) (Category D).
Although consensus guidelines for the general population call for reflex human papillomavirus (HPV) testing for women with ASC-US and colposcopic examination of the cervix for those with evidence of HPV infection, LSIL, and high-grade squamous intraepithelial lesion (HSIL), these guidelines do not apply to adolescents and young women, he said.
The second study found that the NMP179 assay from Matritech (Newton, MA), used to diagnose cervical cancer, identified 92% of high-risk cases among 869 women with Pap smear results that were previously classified as indeterminate (ASCUS) but were later diagnosed with high-grade squamous intraepithelial lesions in follow-up.