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The same technique is also beneficial in patients with acantholytic disorders aggravated by sweat and friction, such as the intertriginous erosive lesions of Hailey-Hailey disease or Darier disease, Dr.
Histologically, the acantholysis seen in Grover disease occurs in a variety of different patterns in small, circumscribed foci resembling Darier-White disease, pemphigus vulgaris, pemphigus foliaceous, Hailey-Hailey disease, and a spongiotic dermatitis.
DIAGNOSIS: Hailey-Hailey disease (benign familial pemphigus).