At the meeting, the agency will ask its Gastrointestinal Drugs Advisory Committee to discuss whether endoscopically documented gastric ulcers are an adequate outcome measure to evaluate drugs that are intended to prevent such NSAID-triggercd GI complications.
What does GU stand for?
GU stands for Gastric Ulcer
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of GU
We have 7 other meanings of GU in our Acronym Attic
- Deutsche Gesellschaft für Technische Zusammenarbeit GmbH (German: German Agency for Technical Cooperation)
- Gostinstvo in Turizem (Slovenian: Catering and Tourism)
- Gallaudet University
- Gamer Unlimited (forum)
- Games Unleashed (online gaming community)
- Gamesunderground (gaming)
- Gaming Union (gaming)
- Gaming Universe
- Gaming Update (forum)
- Gannon University (Pennsylvania)
Samples in periodicals archive:
This was taken as the lowest dose and the efficacy of the test drug was further evaluated in doses of 10, 25 and 50 mg/kg body weight by using aspirin and pyloric ligature induced gastric ulcer models.
2) The most commonly observed adverse events in the clinical trials (experienced by >5% of patients in the VIMOVO group) were erosive gastritis, dyspepsia, gastritis, diarrhea, gastric ulcer, upper abdominal pain and nausea.
In the gastric ulcer induced by hypothermic-restraint stress, both extracts also showed significant activity, and inhibited the gastric lesion index by 58% and 75%, respectively.
Prevacid NapraPAC (lansoprazole delayed-release capsules and naproxen tablets kit) is now approved for reduction of NSAID-associated gastric ulcers in patients with a history of a documented gastric ulcer who require the use of an NSAID for the treatment of the signs and symptoms of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.
Pharmaceutical company Chemeq Ltd (ASX: CMQ) has produced an antimicrobial drug that kills a strain of the gastric ulcer germ, Helicobacter pylori which is resistant to antibiotics.
Gastric ulcers occurred in eight percent of those taking Fosamax, in 12% of those taking only naproxen, but in 38% of those taking both drugs.
Roine notes that people who take aspirin with the gastric ulcer drugs cimetidine or ranitidine may face a double whammy from alcohol, since previous studies have shown that these drugs also reduce gastric alcohol dehydrogenase activity.