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Animals that received pre-treatment with saffron displayed a decrease in the elevation of gamma glutamyl transpeptidase, alanine aminotransferase and alpha-fetoprotein (GGT, ALT, aFP)-proteins, which indicate liver damage.
19 mg/dl, aspartate/alanine aminotransferase (AST/ALT): 162/275 IU/L, gamma glutamyl transpeptidase (GGT): 307 IU, lactate dehydrogenase (LDH): 649 U, HbA1: 53.
Metabolic syndrome is directly associated with gamma glutamyl transpeptidase elevation in Japanese women.
Alkaline phosphatase (ALP) and gamma glutamyl transpeptidase (GGT) values also improved in the GATTEX-treated group versus placebo; however, the difference was not statistically significant.
Importantly, GFT505 had clear statistically significant beneficial effects on two indicators of fatty-liver dysfunction, Alanine Amino Transferase and Gamma Glutamyl Transpeptidase, while it did not affect the plasma level of Aspartate Amino Transferase.