2) First pass metabolism Orally administered drugs pass through the liver before entering the systemic circulation.
What does FPM stand for?
FPM stands for First Pass Metabolism
This definition appears very rarely and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of FPM
We have 147 other meanings of FPM in our Acronym Attic
- Field Production Management
- Field Project Manager
- FIFO and Priority Manager (US Postal Service)
- Filarmónica Portuguesa de Montreal (Portugese)
- Fill-Pattern Monitor (physics)
- Financial Performance Management
- Financial Planning Manager (job title)
- Fine Particulate Matter (diameter less than or equal to 2.5 micrometers)
- Fine Point Mode
- Fire Prediction Model
Samples in periodicals archive:
If THC in Sativex was primarily absorbed through the oral mucosa, bypassing first pass metabolism, we might expect to see a difference between oral THC and Sativex 11-OH-THC/THC ratios; however, no statistical difference was found.
Designed to integrate seamlessly with the Absorption Module, the iDEA(TM) Metabolism Module predicts the extent of human first pass metabolism for a compound.
Transmucosal delivery offers the potential for once daily dosing of oral drugs and avoids the effects of first pass metabolism.
This is an important patent in that it has significant commercial potential for a large number of drug combinations especially where rapid onset and avoiding first pass metabolism may be beneficial.
Applied once daily on one arm from wrist to shoulder, EstroGel(R) avoids first pass metabolism in the liver and minimizes application site skin irritation.
Designed to seamlessly integrate with the Absorption Module, the iDEA(TM) Metabolism Module predicts the extent of first pass metabolism for a compound.
HALO - an alternative oral delivery system to avoid first pass metabolism by the liver and to enhance absorption of poorly bioavailable drugs and to create sustained release formulations of certain kinds of drugs such as testosterone.