What does EC stand for?

About 40% of testicular cancer are seminoma type and the other are divided into four sub-types; choriocarcinoma, teratoma, embryonal carcinoma and yolk sac tumors.

DISCUSSION AND CONCLUSIONS More than two decades ago, it was discovered that when treated with RA, the human embryonal carcinoma cell line NT2 differentiates irreversibly into several morphologically and phenotypically distinct cell types, which include terminally differentiated postmitotic CNS neurons [45-46].

CD30 and c-Kit (CD117) used in combination are known to be useful to distinguish between embryonal carcinoma and seminoma in the gonads.

3) Although intratubular embryonal carcinoma has been described adjacent to invasive embryonal carcinoma, to the best of our knowledge it has not been reported as an isolated finding in human testis.

Human embryonal carcinoma (EC) cells are pluripotent stem cells that provide a novel and robust experimental system for studying cellular differentiation and human embryogenesis, as described in a paper to be published in the August 2004 (Volume 13, Number 4) issue of Stem Cells and Development (formerly Journal of Hematotherapy & Stem Cell Research), a peer-reviewed journal published by Mary Ann Liebert, Inc.

Ki-1 (CD30) antigen is regularly expressed by tumor cells of embryonal carcinoma.

Using a model of human embryonal carcinoma stem cells, the Georgetown/Samaritan Research team screened a number of small molecules for their ability to induce neuronal differentiation.

In addition, the new study demonstrates the ability of RNAi to establish silencing in different mouse cell types including embryonic stem cells, embryonal carcinoma cell lines, and some somatic cells.