For this double-blind, randomized, placebo-controlled study of 93 postmenopausal women (average age - 56 years) subjects drank either one Revival Soy protein shake (20 grams of soy protein with about 160 mg of total soy isofiavones) per day or one placebo shake (20 grams of milk protein with no soy isofiavones) per day for 12 weeks.
This analysis was derived from 52-week study, REVEAL (The Randomized Controlled Evaluation of Adalimumab Every Other Week in Moderate to Severe Psoriasis Trial Abbott Laboratories); this double-blind, randomized, placebo-controlled, phase 3 trial evaluated the safety and efficacy of adalimumab in 1212 patients with moderate to severe chronic psoriasis.
The double-blind, randomized, placebo-controlled, 400-patient study will evaluate the effect of 200 mg of PHX1149, 400 mg of PHX1149, or placebo on hemoglobin A1c levels in patients already receiving metformin, glitazone, or a combination thereof.
In a double-blind, randomized, placebo-controlled study, 16 bipolar disorder patients aged 18-65 with Young Mania Rating Scale (YMRS) scores of 14 or greater after a 2- to 7-day screening period received either tamoxifen (beginning at 20 mg/day and increasing up to 140 mg/day as tolerated) or placebo.
It also reported that while the final design of this trial and the number of patients to be included had not yet been finalized, it anticipated at the time that the trial would be a double-blind, randomized, placebo-controlled trial involving approximately 375 patients.
The Phase I trial of V24343, a CB1 antagonist, will be a double-blind, randomized, placebo-controlled study in overweight and mildly obese volunteers and will be conducted in two parts: a single ascending dose followed by a multiple ascending dose.
Prantera et al conducted a multicenter, double-blind, randomized, placebo-controlled study that enrolled 83 patients with mild to moderate Crohn's disease.
