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Furthermore, we investigate the relationship between CIMT and Hcy levels in PD patients on L-dopa and dopa decarboxylase inhibitor (DDI) treatment.
Single photon emission computed tomography (SPECT) and positron emission tomography (PET) studies have shown that PD patients exhibit decreased levels of dopamine transporters (DATs) and vesicular monoamine transporter type 2 (VMAT2) and reduced activity of dopa decarboxylase as measured by the conversion of L-dopa to dopamine in the striatum using [[.
The same group and others have used the method to characterize the neurochemical profiles of dopamine-|3hydroxylase deficiency, DOPA decarboxylase deficiency, tyrosine hydroxylase deficiency, Menkes disease, and X-linked deficiencies of monoamine oxidase.