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Samples in periodicals archive:
In Detroit, Malia is receiving a new experimental treatment using difluoromethylornithine, or DFMO, which is already approved for use for African sleeping sickness and is being used in cancer trials, since it inhibits a key protein in tumor growth.
Control of nucleic acid and protein synthesis in developing brain, kidney, and heart of the neonatal rat: effects of a difluoromethylornithine, a specific, irreversible inhibitor of' ornithine decarboxvlase.
50] values for diminazene, DL-a- difluoromethylornithine, metronidazole, ornidazole, and suramin in TC221 cells were in a range of 0.
Difluoromethylornithine, an effective new treatment of Gambian trypanosomiasis.
Cells were grown to confluence at which point they were treated with difluoromethylornithine (DFMO), diethylglyoxal bisguanylhydrazone (DEGBG), or a combination of the two.
Difluoromethylornithine, a drug to stop the growth of metastases, severely reduces platelet counts in the blood of cancer patients.
Currently under investigation are epigallocatechin gallate, a green tea catechin with antioxidant, sunscreen, and UVB signal transduction-blocking activity; perillyl alcohol, a monoterpene derived from citrus peel that inhibits Ras farnesylation; difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase and polyamines; retinoids that target retinoid X receptors and AP-1 activity; and nonsteroidal anti-inflammatory agents that inhibit cyclooxygenase and prostaglandin synthesis.