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What does DFMO stand for?

DFMO stands for Difluoromethylornithine

This definition appears very rarely and is found in the following Acronym Finder categories:

  • Science, medicine, engineering, etc.

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We have 2 other definitions for DFMO in our Acronym Attic

Samples in periodicals archive:

In Detroit, Malia is receiving a new experimental treatment using difluoromethylornithine, or DFMO, which is already approved for use for African sleeping sickness and is being used in cancer trials, since it inhibits a key protein in tumor growth.
Control of nucleic acid and protein synthesis in developing brain, kidney, and heart of the neonatal rat: effects of a difluoromethylornithine, a specific, irreversible inhibitor of' ornithine decarboxvlase.
professor of medicine and biological chemistry at the University of California, Irvine, presented late-breaking results from a phase III trial of difluoromethylornithine (DFMO), a synthetic inhibitor of ornithine decarboxylase, and sulindac (Clinoril), an NSAID, in 375 patients.
Agent PK PD (IEB) Antiestrogens Tamoxifen +3 +4 (ER) Raloxifene +4 +4 (ER) Flutamide +2 +4 (AR) NSAI Ds Sulindac +3 +4 (Cox-1/2) R-Flurbiprofen +3 +4 (Cox-1/2) Retinoids 4-HPR +4 +4 (IGF-1, apoptosis) 9-cis-RA +4 +4 (RAR/RXR) 13-cis-RA +4 +4 (RAR/all-trans-RA) Selenium Se-methionine +3 +4 (GSH peroxidase) Dehydroepiandrosterone +4 +4 (Androgenic, estrogenic) Difluoromethylornithine +1 +4 (Polyamines) Agent Issue Antiestrogens Tamoxifen Endometrial CA (+) Raloxifene Endometrial (CA (-) Flutamide Gynecomastia NSAI Ds Sulindac GI toxicity R-Flurbiprofen R > S (anti-CA) Retinoids 4-HPR Night blindness (retinol concns.