For SRT, N-butyl deoxynojirimycin (Zavesca[R]) is approved as an inhibitor of glucosylceramide syntheses enzyme.
What does DNJ stand for?
DNJ stands for Deoxynojirimycin (chemistry)
This definition appears frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of DNJ
We have 4 other meanings of DNJ in our Acronym Attic
- Dialed Number Identification Service
- Dialed Number Information Service
- Disability News and Information Service (India)
- Departamento Nacional de Infra-Estrutura de Transportes (Brazilian government)
- Depth-Node-Input Table
- Detailed Notice Inviting Tender
- Direction Nationale de l'Interprétation et de la Traduction (French: National Directorate for Interpretation and Translation; Benin)
- Daily News Journal (Murfreesboro, TN)
- Dance New Jersey (South Plainfield, NJ)
- Den Norske Jordmorforening (Norwegian: Norwegian Midwife Association)
- Dernières Nouvelles du Jazz (French: Latest News from Jazz)
- Developer Network Journal (Bristol, England, UK)
- Dole Nord Jura (French health association)
- Drone Noise Jammers
- Dynamique Nationale pour la Jeunesse (French: National Youth Dynamic)
- Dil Ne Jise Apna Kahaa (Hindi movie)
- Dodatkowa Nauka Jezyka Bialoruskiego (Polish: Schools with Additional Belarussian)
- Domini Nostri Jesu Christi (Latin: Our Lord Jesus Christ)
- Districts Nazarener Jeugd Internationaal (Dutch: District Nazarene Youth International; religious youth organization)
- Dansk Naturvidenskabeligt Kursussamvirke
Samples in periodicals archive:
Another interesting class of inhibitors such as celgosivir, n-butyl deoxynojirimycin and N-(n-nonyl) deoxynojirimycin target host alpha-glucosidase enzyme and may offer alternative treatment options (131,132).
In substrate reduction therapy (SRT), the synthesis of glycosphingolipids is reduced by partial inhibition of glucosylceramide (G1cCer) synthase by deoxynojirimycin analogs (5), leading to reduction of the glycosphingolipid pool and eventually to reduction of the substrate load for lysosomal degradation by sphingolipid hydrolases.