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What does DMC stand for?

DMC stands for Data Monitoring Committee

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Samples in periodicals archive:

An independent Data Monitoring Committee found that adding Sutent to a chemotherapy regimen as an initial treatment for colon cancer that has spread would be unable to show a statistically significant improvement in progression-free survival compared with the chemotherapy alone, Pfizer said.
com Data Monitoring Committee Recommends Closing Enrollment In Recurrent Glioblastoma STUDY - Other Enzastaurin Trials Unaffected - INDIANAPOLIS, DECEMBER 21, 2006 - After reviewing data gathered to date, as part of a planned interim analysis, an External Data Monitoring Committee (DMC) has recommended that the STEERING trial (Study Evaluating Enzastaurin in Recurrent Glioblastoma) be closed for enrollment.
Helsinn reported that despite some evidence of becatecarin activity, preliminary analysis of the Phase III data by an Independent Data Monitoring Committee indicated that the comparator agent 5-fluorouracil (5-FU) demonstrated a greater than expected survival benefit, making it statistically improbable that the final study results could achieve the planned objectives for the trial.
The authors also criticize the adversarial yet symbiotic relationships between IRBs and data monitoring committees, which sometimes are used to independently assess a study and protect test subjects, thereby putting them in the position of both acting as watchdog and working to keep a study on track.