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Each of the extracts was tested for its ability to inhibit the key pro-inflammatory enzymes - cyclooxygenase 1 [COX1], cyclooxygenase 2 [COX2], and 5-lipooxygenase [5-LOX] - that are known contributors to impaired joint health, pain, and arthritis.
Seibert K, Zhang Y, Leahy K, et al: Pharmacologic and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.