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When mice were fed a selenium-deficient diet and then inoculated with a nonvirulent strain of Coxsackievirus B3, the virus mutated to become a virulent strain.
Coxsackievirus B3 (CVB3) (family Picornaviridae, genus Enterovirus) is a major human pathogen (1-3), and CVB3-associated aseptic meningitis is an emerging concern (4).
First, the antiviral effects of salidroside against coxsackievirus B3 (CVB3) were determined in vitro and in vivo.
Coxsackievirus B3, Shandong Province, China, 1990-2010.
The evidence of coxsackievirus B3 induced myocarditis as the cause of death in a Sichuan snub-nosed monkey (Rhinopithecus roxellana).
For example, coxsackievirus B3 (CB3) infection of susceptible mice results in inflammation of the heart (myocarditis) that resembles myocarditis in humans.
For example, coxsackievirus B3 induces viral myocarditis in susceptible mice.