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Liver Copper transporter ctrl mRNA was not correlated with liver Cu concentrations in all three species (Table 3).
Intracellular copper binds to various cytosolic chaperone proteins and then is pumped into the trans-Golgi endoplasmic reticulum via the copper transporter ATP7A (copper-transporting ATPase 1).
Nir Ben-Tal, Maya Schushan and Yariv Barkan of TAU and Turkan Haliloglu of Bogazici University in Istanbul, created a computational model demonstrating the structure, motion and function of hCTR1 (Human Copper Transporter 1) - a protein found in the membrane of human cells, and responsible for transporting copper ions through the membrane.